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Home › Dataset Library › Integrated bioinformatic and wet-lab approach to identify potential oncogenic networks in neuroblastoma: MEIS1

Dataset: Integrated bioinformatic and wet-lab approach to identify potential oncogenic networks in neuroblastoma: MEIS1

The pediatric tumor neuroblastoma is the second cause of cancer-related death in children. Although several recurrent gene aberrations...

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The pediatric tumor neuroblastoma is the second cause of cancer-related death in children. Although several recurrent gene aberrations have been found, the main signaling networks in the neuroblastoma cell, that can give important clues for more specific, more efficient treatment, is still unknown. Here we demonstrate an analysis of the MEIS1 pathway in neuroblastic tumors. It suggests important regulatory connections to tumor differentiation, cell cycle, and cell death. Time-course experiment of MEIS1-shRNA induction, with 5 timepoints.

Species:
human

Samples:
5

Source:
E-GEOD-17827

Updated:
Dec.12, 2014

Registered:
Sep.15, 2014


Factors: (via ArrayExpress)
Sample INDUCTION TIME DOXYCYCLINE INDUCTION
GSM444777 0h no
GSM444778 24h yes
GSM444779 48h yes
GSM444780 96h yes
GSM44478 192h yes

Tags

  • cancer
  • cell
  • neuroblastoma

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