{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "mouse", "factors": [{"GSE17647GSM440309": {}}, {"GSE17647GSM440310": {}}, {"GSE17647GSM440311": {}}, {"GSE17647GSM440312": {}}, {"GSE17647GSM440313": {}}, {"GSE17647GSM440314": {}}, {"GSE17647GSM440315": {}}, {"GSE17647GSM440316": {}}, {"GSE17647GSM440317": {}}, {"GSE17647GSM440318": {}}, {"GSE17647GSM440319": {}}, {"GSE17647GSM440320": {}}, {"GSE17647GSM440321": {}}, {"GSE17647GSM440322": {}}, {"GSE17647GSM440323": {}}, {"GSE17647GSM440324": {}}, {"GSE17647GSM440325": {}}, {"GSE17647GSM440326": {}}, {"GSE17647GSM440327": {}}, {"GSE17647GSM440328": {}}, {"GSE17647GSM440329": {}}, {"GSE17647GSM440330": {}}, {"GSE17647GSM440331": {}}, {"GSE17647GSM440332": {}}], "id": 5788, "pop_total": 0, "platform": 6, "summary_wrapped": "High-density lipoproteins (HDLs) protect pancreatic \u03b2 cells against apoptosis. This property might be related to the increased risk to...", "geo_gse_id": "E-GEOD-17647", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 24, "tags": [], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-human-pancreatic-beta-c", "geo_id_plat": "E-GEOD-17647_A-AFFY-45", "name": "Transcription profiling of human pancreatic beta cells reveals the involvement of 4E-BP1 in the protection induced by HDLs", "created": "Nov.11, 2014", "summary": "High-density lipoproteins (HDLs) protect pancreatic \u03b2 cells against apoptosis. This property might be related to the increased risk to develop diabetes in patients with low HDL blood levels. However, the mechanisms by which HDLs protect \u03b2 cells are poorly characterized. Here we use a transcriptomic approach to identify genes differentially modulated by HDLs in \u03b2 cells subjected to apoptotic stimuli. Experiment Overall Design: Tested conditions on beta-TC3 cells for 6h (in triplicates for each condition; GSK3 and GSK4 indicate two independent HDL preparations): Experiment Overall Design: Complete Medium + Vehicle [V] Experiment Overall Design: Complete Medium + HDL (prep. HDL GSK3 or HDL GSK4) [HDL] Experiment Overall Design: Starvation medium + Vehicle [V.S] Experiment Overall Design: Starvation medium + HDL (prep. HDL GSK3 or HDL GSK4) [HDL.S]", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-17647", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-17647/samples/"}