ArrayExpress Uploader0humanMale 45HBV positiveMale 45HBV positiveMale 66HBV positiveMale 65HBV positiveFemale 52HCV positiveFemale 52HCV positiveMale 69HBV positiveFemale 48HBV positivemalenot specifiedmalenot specifiedmalenot specifiedmalenot specifiedMale 52HBV positiveMale 48HBV positiveMale 50HBV positiveMale 64HBV positiveMale 41HBV+HDV positiveMale 62HCV positiveMale 41HBV+HDV positiveMale 60HBV positiveMale 60HBV positivefemalenot specifiedMale 64HCV positiveFemale 44not specifiedFemale 44not specifiedMale 59HBV positiveMale 52HBV positiveMale 52HBV positivemalenot specifiedMale 56HBV positiveMale 56HBV positiveFemale 30HBV positiveMale 62HCV positiveMale 62HCV positiveMale 49HBV positiveMale 50HBV positiveMale 50HBV positive2432arrayexpress_sid4Hepatocellular carcinoma (HCC) is the fifth most-common cancer worldwide causing nearly 600,000 deaths esch year. Approximately 80% of...23691139E-GEOD-17548/profile/8773/arrayexpressuploader237cancercarcinomacirrhosishepatocellular carcinomaliquidliverDec.12, 2014FalseE-GEOD-17548_A-AFFY-44expression-data-from-cirrhosis-and-hcc-tissue-sampExpression data from cirrhosis and HCC tissue samplesJul.12, 2014Hepatocellular carcinoma (HCC) is the fifth most-common cancer worldwide causing nearly 600,000 deaths esch year. Approximately 80% of HCC develops on the background of cirrhosis.It is necessary to identify novel genes involved in HCC to implement new diagnostic and treatment options. However, the molecular pathogenesis of HCC largely remains unsolved. Only a few genetic alterations, namely those affecting p53, β-catenin and p16INK4a have been implicated at moderate frequencies of these cancers. Early detection of HCC with appropriate treatment can decrease tumor-related deaths We used microarrays to detail the global programme of gene expression profiles of cirrhosis and tumor liver samples. 15 cirrhosis and 15 HCC samples were collected with informed constent of each patient. Surgically resected tissues were snap frozen in liquid nitrogen and stored at -80C, and subjected to RNA extraction. Histology slides were prepared for all samples and scored by an experienced scientist. For the tumor samples, tissues were resected from inside the tumor, while tissues were resected from adjacent tissue sorrounding the tumor for non-tumor samples.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-17548http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-17548/samples/