ArrayExpress Uploader03325FACS sorted leukemic blasts from patientsnot specifiedDown Syndrome-AMKLFACS sorted leukemic blasts from patientsnot specifiedDown Syndrome-AMKLFACS sorted leukemic blasts from patientsnot specifiedDown Syndrome-AMKLFACS sorted leukemic blasts from patientsnot specifiedDown Syndrome-AMKLFACS sorted leukemic blasts from patientsnot specifiedDown Syndrome-AMKLFACS sorted leukemic blasts from patientsnot specifiedDown Syndrome-AMKLFACS sorted leukemic blasts from patientsnot specifiedAMKLFACS sorted leukemic blasts from patientsnot specifiedAMKLFACS sorted leukemic blasts from patientsnot specifiedAMKLFACS sorted leukemic blasts from patientsnot specifiedAMKLFACS sorted leukemic blasts from patientsnot specifiedAMKLAMKL cell lineUT-7not specifiedDS-AMKL cell lineCMKnot specifiedAMKL cell lineUT-7not specifiedDS-AMKL cell lineCMKnot specifiedAMKL cell lineMEG01not specifiedAMKL cell lineM07not specifiedErythroleukemia cell lineK562not specifiedarrayexpress_sid4The goal of this study is to define a gene expression signature unique to DS-AMKL (acute megakaryoblastic leukemia or FAB M7 leukemia). A...20679399E-GEOD-16677/profile/8773/arrayexpressuploader318leukemiamegakaryocytic leukemiaDec.12, 2014Falsegene-expression-profiling-of-down-syndrome-ds-amklE-GEOD-16677_A-AFFY-44Gene expression profiling of Down Syndrome (DS)-AMKL and non-DS AMKL samplesSep.12, 2014The goal of this study is to define a gene expression signature unique to DS-AMKL (acute megakaryoblastic leukemia or FAB M7 leukemia). A similar study was done previously, but using unfractionated patient leukemic samples. In this study, we sorted megakaryocytic leukemia blasts from patients and then compared their gene expression signatures to those from similarly sorted blasts from patients with non-DS AMKL. This allowed us to identify a gene expression signature more unique to DS-AMKL samples. The leukemic blasts were sorted based on CD41, CD7, CD117, CD33, and CD34 antibodies as previously described (Klin. Padiatr. 217, 126-134).http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-16677humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-16677/samples/