{"platform": 3, "owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM4159": {"CELL LINE": "2274"}}, {"GSM415908": {"CELL LINE": "2295"}}, {"GSM415917": {"CELL LINE": "4142"}}, {"GSM415907": {"CELL LINE": "2293"}}, {"GSM415915": {"CELL LINE": "SCP6"}}, {"GSM415906": {"CELL LINE": "4175"}}, {"GSM415916": {"CELL LINE": "SCP26"}}, {"GSM415910": {"CELL LINE": "1833"}}, {"GSM415918": {"CELL LINE": "4173"}}, {"GSM415910": {"CELL LINE": "1833"}}, {"GSM415920": {"CELL LINE": "4180"}}, {"GSM415902": {"CELL LINE": "MDA-MB-231"}}, {"GSM415910": {"CELL LINE": "1833"}}, {"GSM415909": {"CELL LINE": "2297"}}, {"GSM415912": {"CELL LINE": "2268"}}, {"GSM415914": {"CELL LINE": "SCP21"}}, {"GSM415913": {"CELL LINE": "2269"}}, {"GSM415906": {"CELL LINE": "4175"}}, {"GSM415906": {"CELL LINE": "4175"}}], "id": 1361, "ownerprofile_id": "arrayexpress_sid", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-16554", "summary_wrapped": "MDA-MB-231 bone-metastatic subline 1833 and lung metastatic subline 4175 underwent spontaneous ploidy doubling in culture, i.e. the...", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 19, "tags": ["bone", "cell", "genome", "line", "lung"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "enhancement-of-metastasis-by-spontaneous-ploidy-do", "geo_id_plat": "E-GEOD-16554_A-AFFY-33", "name": "Enhancement of metastasis by spontaneous ploidy doubling of breast cancer cell MDA-MB-231.", "created": "Jun.19, 2014", "summary": "MDA-MB-231 bone-metastatic subline 1833 and lung metastatic subline 4175 underwent spontaneous ploidy doubling in culture, i.e. the genome approximately duplicated itself gradually. The modal- and hyper-ploid subpopulations during the ploidy transition were sorted into two separate sublines, 1833-Modal and 1833-Hyper for 1833, 4175-Modal and 4175-Hyper for 4175. Their expresssion patterns were compared to each other as well as to other MDA-MB-231 sublines isolated previously by Kang et al. 2003 and Minn et al. 2005.  Keywords: Cell type comparison 19 cell lines were analyzed, including the parental line MDA-MB-231, modal-ploid sublines 1833-Modal and 4175-Modal, hyper-ploid sublines 1833-Hyper and 4175-Hyper, strongly bone-metastatic lines 1833 (the original subline after short culture), 2274, 2268 and 2269, weakly bone-metastatic lines 2293, 2295 and 2297, strongly lung-metastaic lines 4142, 4173, 4175 (the original subline after short culture) and 4180, and weakly lung-metastatic lines SCP6, SCP21 and SCP26. Single sample for each line.", "geo_gse_id": "E-GEOD-16554", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-16554/samples/"}