ArrayExpress Uploader0humanNormal lymphoid cellsNormal lymphoid cellsLesional myeloid cellsLesional blastic cellsNormal lymophoid cellsNormal lymophoid cellsNormal lymophoid cellsLesional erythroid cellsLesional blastic cellsNormal lymphoid cellsNormal lymophoid cellsLesional blastic cellsLesional myeloid cellsLesional myeloid cells3292arrayexpress_sid4Myelodysplastic Syndromes (MDSs) are a heterogeneous family of clonal disorders of hematopoietic stem cells characterized by ineffective...E-GEOD-16236/profile/8773/arrayexpressuploader114bonebone marrowgenomeleukemiaDec.12, 2014Falsetranscriptional-profiling-of-bone-marrow-cells-ofE-GEOD-16236_A-AFFY-44Transcriptional profiling of bone marrow cells of MDS patientsSep.12, 2014Myelodysplastic Syndromes (MDSs) are a heterogeneous family of clonal disorders of hematopoietic stem cells characterized by ineffective hematopoiesis and frequently leukemia progression. To exlore how MDS develop into leukemia, we performed the transcriptional profiling of lesional cells and normal lymphoid cells from the MDS patients. Bone marrow cells from the MDS patients were sorted into blastic, myeloid, erythroid and lymphoid fractions by flow cytometry and then were profiled transcriptionally by Human Human Genome U133 Plus 2.0 arrays. Differentially expressed genes between lesional cells and lymphoid cells were identified by SAM.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-16236http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-16236/samples/