Dataset: Expression data from lung of mice bearing mutations of FGFR3 and FGFR4
Gene expression profiling of newborn lung tissue revealed few changes in compound FGFR3/FGFR4 deficient mice, consistent with their...
Gene expression profiling of newborn lung tissue revealed few changes in compound FGFR3/FGFR4 deficient mice, consistent with their normal lung morphology at birth, suggesting the sequence of events leading to the phenotype initiates after birth in this model. Profiling of 4 week-old lung tissues revealed an induction of genes related to elastic fiber assembly in compound mutants. Lung RNA isolated from three animals of each genotype-age group were pooled for each Affymetrix chip (n=3 chips for each, except n=2 for wild type at 4 weeks.
- Species:
- mouse
- Samples:
- 26
- Source:
- E-GEOD-15452
- PubMed:
- 20093646
- Updated:
- Dec.12, 2014
- Registered:
- Nov.11, 2014
Factors:
(via ArrayExpress)
| Sample | age | genotype |
|---|---|---|
| GSM387650 | 28 | FGFR3 and FGFR4 double heterozygous mutant |
| GSM387650 | 28 | FGFR3 and FGFR4 double heterozygous mutant |
| GSM387650 | 28 | FGFR3 and FGFR4 double heterozygous mutant |
| GSM387653 | 28 | FGFR3 and FGFR4 double knockout |
| GSM387653 | 28 | FGFR3 and FGFR4 double knockout |
| GSM387653 | 28 | FGFR3 and FGFR4 double knockout |
| GSM387656 | 28 | wild type genotype |
| GSM387656 | 28 | wild type genotype |
| GSM387658 | 1 | FGFR3 and FGFR4 double heterozygous mutant |
| GSM387658 | 1 | FGFR3 and FGFR4 double heterozygous mutant |
| GSM387658 | 1 | FGFR3 and FGFR4 double heterozygous mutant |
| GSM38766 | 1 | FGFR3 and FGFR4 double knockout |
| GSM38766 | 1 | FGFR3 and FGFR4 double knockout |
| GSM38766 | 1 | FGFR3 and FGFR4 double knockout |
| GSM387664 | 1 | wild type genotype |
| GSM387664 | 1 | wild type genotype |
| GSM387664 | 1 | wild type genotype |
| GSM387667 | 8 | FGFR3 and FGFR4 double heterozygous mutant |
| GSM387667 | 8 | FGFR3 and FGFR4 double heterozygous mutant |
| GSM387667 | 8 | FGFR3 and FGFR4 double heterozygous mutant |
| GSM387670 | 8 | FGFR3 and FGFR4 double knockout |
| GSM387670 | 8 | FGFR3 and FGFR4 double knockout |
| GSM387670 | 8 | FGFR3 and FGFR4 double knockout |
| GSM387673 | 8 | wild type genotype |
| GSM387673 | 8 | wild type genotype |
| GSM387673 | 8 | wild type genotype |