Dataset: Transcription profiling of human whole blood from rheumatoid arthritis patients
The whole blood was collected pre-treatment from rheumatoid arthritis patients starting the anti_TNF therapy. All patients were naïve to...
The whole blood was collected pre-treatment from rheumatoid arthritis patients starting the anti_TNF therapy. All patients were naïve to anti_TNFs. The disease activity was measured using the DAS28 score at the pre-treatment visit1 (DAS28_v1) and 14 weeks after treatment visit3 (DAS28_v3). The response to the therapy was evaluated using the EULAR [European League Against Rheumatism] definition of the response. The objective of the data analysis was to identify gene expression coorelating with response as well as to identify genes that differentiate responders versus non-responders pre-treatment. The results of this investigation identified 8 trainscripts that predict responders vs. non-responders with 89% accuracy. Experiment Overall Design: Patients' response to anti-TNF was assessed using EULAR score and patients were classified as responders, moderate responders and non-responders. Genes correlating with the response status have been identified.
- Species:
- human
- Samples:
- 86
- Source:
- E-GEOD-15258
- PubMed:
- 19699293
- Updated:
- Dec.12, 2014
- Registered:
- Sep.12, 2014
Sample |
---|
GSE15258GSM381194 |
GSE15258GSM381195 |
GSE15258GSM381196 |
GSE15258GSM381197 |
GSE15258GSM381198 |
GSE15258GSM381199 |
GSE15258GSM381200 |
GSE15258GSM381201 |
GSE15258GSM381202 |
GSE15258GSM381203 |
GSE15258GSM381204 |
GSE15258GSM381205 |
GSE15258GSM381206 |
GSE15258GSM381207 |
GSE15258GSM381208 |
GSE15258GSM381209 |
GSE15258GSM381210 |
GSE15258GSM381211 |
GSE15258GSM381212 |
GSE15258GSM381213 |
GSE15258GSM381214 |
GSE15258GSM381215 |
GSE15258GSM381216 |
GSE15258GSM381217 |
GSE15258GSM381218 |
GSE15258GSM381219 |
GSE15258GSM381220 |
GSE15258GSM381221 |
GSE15258GSM381222 |
GSE15258GSM381223 |
GSE15258GSM381224 |
GSE15258GSM381225 |
GSE15258GSM381226 |
GSE15258GSM381227 |
GSE15258GSM381228 |
GSE15258GSM381229 |
GSE15258GSM381230 |
GSE15258GSM381231 |
GSE15258GSM381232 |
GSE15258GSM381233 |
GSE15258GSM381234 |
GSE15258GSM381235 |
GSE15258GSM381236 |
GSE15258GSM381237 |
GSE15258GSM381238 |
GSE15258GSM381239 |
GSE15258GSM381240 |
GSE15258GSM381241 |
GSE15258GSM381242 |
GSE15258GSM381243 |
GSE15258GSM381244 |
GSE15258GSM381245 |
GSE15258GSM381246 |
GSE15258GSM381247 |
GSE15258GSM381248 |
GSE15258GSM381249 |
GSE15258GSM381250 |
GSE15258GSM381251 |
GSE15258GSM381252 |
GSE15258GSM381253 |
GSE15258GSM381254 |
GSE15258GSM381255 |
GSE15258GSM381256 |
GSE15258GSM381257 |
GSE15258GSM381258 |
GSE15258GSM381259 |
GSE15258GSM381260 |
GSE15258GSM381261 |
GSE15258GSM381262 |
GSE15258GSM381263 |
GSE15258GSM381264 |
GSE15258GSM381265 |
GSE15258GSM381266 |
GSE15258GSM381267 |
GSE15258GSM381268 |
GSE15258GSM381269 |
GSE15258GSM381270 |
GSE15258GSM381271 |
GSE15258GSM381272 |
GSE15258GSM381273 |
GSE15258GSM381274 |
GSE15258GSM381275 |
GSE15258GSM381276 |
GSE15258GSM381277 |
GSE15258GSM381278 |
GSE15258GSM381279 |