ArrayExpress Uploaderarrayexpress_sidhuman316504Rhabdomyosarcomas (RMS) are characterized by expression of myogenic specification genes, such as MyoD and/or Myf5, as well as their bHLH...E-GEOD-14825/profile/8773/arrayexpressuploader06cellserumDec.12, 2014FalseE-GEOD-14825_A-AFFY-44transcription-profiling-of-human-rhabdomyosarcomaTranscription profiling of human rhabdomyosarcoma cells expressing Myod and E-protein heterodimer and controlsSep.11, 2014Rhabdomyosarcomas (RMS) are characterized by expression of myogenic specification genes, such as MyoD and/or Myf5, as well as their bHLH partners for heterodimerization, the E-proteins. We have shown that expression of a forced heterodimer of MyoD with one of the E2A proteins, E12, leads to differentiation in a RMS cell culture model when exposed to low serum conditions. Experiment Overall Design: RD cells (a type of RMS) were retrovirally infected with either the MyoD~E heterodimer or an empty control vector, differentiated for 24 hours and then RNA collected.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14825http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14825/samples/