Dataset: Immune Response of Immature Dendritic Cells after Infection with Human Cytomegalovirus Strain TB40E

Microarray analysis and quantitative real-time PCR revealed that TB40E infection of DCs led to changes of the gene expression pattern. A variety of pro-inflammatory cytokines and chemokines (CXCL10, CXCL11, CCL5), TLR3 and genes whose products function downstream of the TLR3 signalling pathway (e.g. IFN-α, IFN-β) were significantly upregulated. three mock transfected DC vs. three TB40 transfected DCs

Species:

human

Samples:

6

Source:

E-GEOD-14816

PubMed:

19951172

Updated:

Dec.12, 2014

Registered:

Jun.19, 2014