ArrayExpress Uploaderarrayexpress_sidmouse839208Growing evidence indicates that PPARγ agonists, such as rosiglitazone (RSG,), induce adipose mitochondrial biogenesis. Using microarrays,...E-GEOD-14810/profile/8773/arrayexpressuploader071adipocyteDec.12, 2014FalseE-GEOD-14810_A-AFFY-36transcription-profiling-of-mouse-c3h10t12-and-3t3Transcription profiling of mouse C3H/10T1/2 and 3T3 L1 adipocytesNov.24, 2014Growing evidence indicates that PPARγ agonists, such as rosiglitazone (RSG,), induce adipose mitochondrial biogenesis. Using microarrays, we systematically analyzed nucleus-encoded mitochondrial gene expression in two common murine adipocyte models, 3T3 L1 and C3H/10T1/2 adipocytes, and aimed to further establish the direct role of RSG, and capture the temporal changes in mitochondrial gene transcription during this process. Experiment Overall Design: Fully differentiated 3T3 L1 and C3H/10T1/2 adipocytes were treated with RSG, or DMSO vehicle for 1, 2, 4, 7, 24, and 48 hrs, and total RNA was extracted for microarray analysis.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14810http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14810/samples/