{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM370545 1": {}}, {"GSM370550 1": {}}, {"GSM370551 1": {}}, {"GSM370552 1": {}}, {"GSM370553 1": {}}, {"GSM370554 1": {}}, {"GSM370555 1": {}}, {"GSM370556 1": {}}], "id": 3164, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "The therapeutic potential of pro-resolution factors in determining the outcome of inflammatory events has gained ground over the past...", "pubmed_id": 20862244, "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 8, "tags": ["protein"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "investigation-of-over-expressing-annexin-receptor", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14807", "geo_id_plat": "E-GEOD-14807_A-AFFY-44", "name": "Investigation of over-expressing Annexin receptor cell line with and without agonists", "created": "Sep.11, 2014", "summary": "The therapeutic potential of pro-resolution factors in determining the outcome of inflammatory events has gained ground over the past decade. However, the attention has been focused on the non-genomic effects of these endogenous, anti-inflammatory substances. In this study, we have focused our attention on identifying specific annexin 1 (AnxA1) protein/ALX receptor mediated gene activation, in an effort to identify down-stream genomic targets of this well-known, glucocorticoid induced, pro-resolution factor. In this study, we used four different types of samples (with 2 replicates each):1)cells transfected with the empty pGEX-4T-327 vector and vehicle (PBS) treated; 2)cells transfected with the annexin receptor ALXR (also known as FPR2) and vehicle (PBS) treated; 3)cells transfected with the annexin receptor ALXR and treated with 10uM Ac-26 peptide for 4 hours; 4) cells transfected with the annexin receptor ALXR and treated with 0.5uM Annexin 1 for 4 hours. After the treatments, cells were collected for RNA extraction.", "geo_gse_id": "E-GEOD-14807", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14807/samples/"}