ArrayExpress Uploader08388arrayexpress_sid8This is a comparative microarray analysis of LE-AP-2a mutants vs. wild-type P0 littermate lenses. This analysis revealed differential...18224708E-GEOD-14536/profile/8773/arrayexpressuploader06cadherincellcell phenotypee-cadherinepithelial celllenslens epithelial cellDec.12, 2014Falsetranscription-profiling-of-mouse-le-ap-2a-mutantsE-GEOD-14536_A-AFFY-36Transcription profiling of mouse LE-AP-2a mutants vs. wild-type P0 littermate lenses to investigate cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype.Nov.24, 2014This is a comparative microarray analysis of LE-AP-2a mutants vs. wild-type P0 littermate lenses. This analysis revealed differential gene expression of 415 mRNAs, including reduced expression of genes important for maintaining lens epithelial cell phenotype, such as E-cadherin. Experiment Overall Design: Biological triplicates of mouse lenses were analyzed (three wild-type lens samples and three Le-AP-2 mutant samples)http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14536mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14536/samples/