ArrayExpress Uploader0humangrade 3conventional ostosarcoma tissueosteosarcomafemurfemalegrade 3conventional ostosarcoma tissueosteosarcomafemurfemalegrade 2conventional ostosarcoma tissueosteosarcomafemurfemalegrade 2conventional ostosarcoma tissueosteosarcomafemurfemalegrade 3conventional ostosarcoma tissueosteosarcomafemurmalegrade 3conventional ostosarcoma tissueosteosarcomafemurmalegrade 3conventional ostosarcoma tissueosteosarcomatibiamalegrade 3conventional ostosarcoma tissueosteosarcomatibiamalegrade 2conventional ostosarcoma tissueosteosarcomafemurmalegrade 2conventional ostosarcoma tissueosteosarcomafemurmale Non-neoplastic primary osteoblast cells with limited live span in vitronormal Non-neoplastic primary osteoblast cells with limited live span in vitronormal grade 3metastatis tissueosteosarcomalungfemalegrade 3metastatis tissueosteosarcomalungfemalegrade 2metastatis tissueosteosarcomalungfemalegrade 2metastatis tissueosteosarcomalungfemalegrade 1metastatis tissueosteosarcomalungfemalegrade 1metastatis tissueosteosarcomalungfemalegrade 3metastatis tissueosteosarcomalungmalegrade 3metastatis tissueosteosarcomalungmale1344arrayexpress_sid3In osteosarcoma patients, the development of metastases, often to the lungs, is the most frequent cause of death. To improve this...E-GEOD-14359/profile/8773/arrayexpressuploader520conventional osteosarcomalungosteoblastosteosarcomaDec.12, 2014Falsetranscription-profiling-by-array-of-human-conventiE-GEOD-14359_A-AFFY-33Transcription profiling by array of human conventional osteosarcoma and primary non-neoplastic osteoblast cellsJun.19, 2014In osteosarcoma patients, the development of metastases, often to the lungs, is the most frequent cause of death. To improve this situation, a deeper understanding of the molecular mechanisms governing osteosarcoma development and dissemination and the identification of novel drug targets for an improved treatment are needed. Towards this aim, we characterized osteosarcoma tissue samples compared to primary osteoblast cells using Affymetrix HG U133A microarrays. mRNA from 5 frozen conventional osteosarcoma and 4 osteosarcoma lung metastases tumor samples and mRNA from fresh primary osteoblast cells were extracted and hybridized to HG U133A microarrays.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14359http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14359/samples/