{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM359139": {"disease state": "osteosarcoma", "clinical information": "conventional ostosarcoma tissue", "sex": "female", "organism part": "femur", "tumor grading": "grade 3"}}, {"GSM359139": {"disease state": "osteosarcoma", "clinical information": "conventional ostosarcoma tissue", "sex": "female", "organism part": "femur", "tumor grading": "grade 3"}}, {"GSM359143": {"disease state": "osteosarcoma", "clinical information": "conventional ostosarcoma tissue", "sex": "female", "organism part": "femur", "tumor grading": "grade 2"}}, {"GSM359143": {"disease state": "osteosarcoma", "clinical information": "conventional ostosarcoma tissue", "sex": "female", "organism part": "femur", "tumor grading": "grade 2"}}, {"GSM359149": {"disease state": "osteosarcoma", "clinical information": "conventional ostosarcoma tissue", "sex": "male", "organism part": "femur", "tumor grading": "grade 3"}}, {"GSM359149": {"disease state": "osteosarcoma", "clinical information": "conventional ostosarcoma tissue", "sex": "male", "organism part": "femur", "tumor grading": "grade 3"}}, {"GSM359155": {"disease state": "osteosarcoma", "clinical information": "conventional ostosarcoma tissue", "sex": "male", "organism part": "tibia", "tumor grading": "grade 3"}}, {"GSM359155": {"disease state": "osteosarcoma", "clinical information": "conventional ostosarcoma tissue", "sex": "male", "organism part": "tibia", "tumor grading": "grade 3"}}, {"GSM359147": {"disease state": "osteosarcoma", "clinical information": "conventional ostosarcoma tissue", "sex": "male", "organism part": "femur", "tumor grading": "grade 2"}}, {"GSM359147": {"disease state": "osteosarcoma", "clinical information": "conventional ostosarcoma tissue", "sex": "male", "organism part": "femur", "tumor grading": "grade 2"}}, {"GSM359137": {"disease state": "normal", "clinical information": "Non-neoplastic primary osteoblast cells with limited live span in vitro", "sex": "  ", "organism part": "  ", "tumor grading": "    "}}, {"GSM359137": {"disease state": "normal", "clinical information": "Non-neoplastic primary osteoblast cells with limited live span in vitro", "sex": "  ", "organism part": "  ", "tumor grading": "    "}}, {"GSM359154": {"disease state": "osteosarcoma", "clinical information": "metastatis tissue", "sex": "female", "organism part": "lung", "tumor grading": "grade 3"}}, {"GSM359154": {"disease state": "osteosarcoma", "clinical information": "metastatis tissue", "sex": "female", "organism part": "lung", "tumor grading": "grade 3"}}, {"GSM359146": {"disease state": "osteosarcoma", "clinical information": "metastatis tissue", "sex": "female", "organism part": "lung", "tumor grading": "grade 2"}}, {"GSM359146": {"disease state": "osteosarcoma", "clinical information": "metastatis tissue", "sex": "female", "organism part": "lung", "tumor grading": "grade 2"}}, {"GSM359142": {"disease state": "osteosarcoma", "clinical information": "metastatis tissue", "sex": "female", "organism part": "lung", "tumor grading": "grade 1"}}, {"GSM359142": {"disease state": "osteosarcoma", "clinical information": "metastatis tissue", "sex": "female", "organism part": "lung", "tumor grading": "grade 1"}}, {"GSM359152": {"disease state": "osteosarcoma", "clinical information": "metastatis tissue", "sex": "male", "organism part": "lung", "tumor grading": "grade 3"}}, {"GSM359152": {"disease state": "osteosarcoma", "clinical information": "metastatis tissue", "sex": "male", "organism part": "lung", "tumor grading": "grade 3"}}], "id": 1344, "pop_total": 0, "platform": 3, "summary_wrapped": "In osteosarcoma patients, the development of metastases, often to the lungs, is the most frequent cause of death. To improve this...", "geo_gse_id": "E-GEOD-14359", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 5, "sample_count": 20, "tags": ["conventional osteosarcoma", "lung", "osteoblast", "osteosarcoma"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-by-array-of-human-conventi", "geo_id_plat": "E-GEOD-14359_A-AFFY-33", "name": "Transcription profiling by array of human conventional osteosarcoma and primary non-neoplastic osteoblast cells", "created": "Jun.19, 2014", "summary": "In osteosarcoma patients, the development of metastases, often to the lungs, is the most frequent cause of death. To improve this situation, a deeper understanding of the molecular mechanisms governing osteosarcoma development and dissemination and the identification of novel drug targets for an improved treatment are needed. Towards this aim, we characterized osteosarcoma tissue samples compared to primary osteoblast cells using Affymetrix HG U133A microarrays. mRNA from 5 frozen conventional osteosarcoma and 4 osteosarcoma lung metastases tumor samples and mRNA from fresh primary osteoblast cells were extracted and hybridized to HG U133A microarrays.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14359", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-14359/samples/"}