{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "id": 8225, "factors": [{"GSM344602": {"TREATMENT": "control", "DIET": "standard"}}, {"GSM344602": {"TREATMENT": "control", "DIET": "standard"}}, {"GSM344602": {"TREATMENT": "control", "DIET": "standard"}}, {"GSM344605": {"TREATMENT": "TNBS", "DIET": "standard"}}, {"GSM344605": {"TREATMENT": "TNBS", "DIET": "standard"}}, {"GSM344605": {"TREATMENT": "TNBS", "DIET": "standard"}}, {"GSM344608": {"TREATMENT": "control", "DIET": "2% curcumin"}}, {"GSM344608": {"TREATMENT": "control", "DIET": "2% curcumin"}}, {"GSM344608": {"TREATMENT": "control", "DIET": "2% curcumin"}}, {"GSM3446": {"TREATMENT": "TNBS", "DIET": "2% curcumin"}}, {"GSM3446": {"TREATMENT": "TNBS", "DIET": "2% curcumin"}}, {"GSM3446": {"TREATMENT": "TNBS", "DIET": "2% curcumin"}}], "pop_total": 0, "platform": 7, "summary_wrapped": "Curcumin is a potent anti-inflammatory compound capable of preventing chemically induced colitis in mice. We used microarray analysis to...", "pubmed_id": 18200517, "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 12, "tags": ["colitis", "colon", "disease"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-13705_A-AFFY-23", "slug": "the-effects-of-dietary-curcumin-on-colonic-gene-ex", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-13705", "geo_gds_id": "", "name": "The effects of dietary curcumin on colonic gene expression in TNBS-induced colitis", "created": "Nov.23, 2014", "summary": "Curcumin is a potent anti-inflammatory compound capable of preventing chemically induced colitis in mice. We used microarray analysis to detail the global programme of colonic gene expression in BALB/c mice fed standard or 2% curcumin-supplemented diet and treated with control or TNBS (trnitrobenzene-sulfonic acid, 2 mg/mouse) enema.  Keywords: Diet and disease effect. 6-8 week old BALB/c mice were treated with respecive diet two days prior to enema administration (day 0) and sacrificed on day 7. Whole colon was dissected from  mice and their wild-type littermates and total RNA isolated for microarray analysis using Affymetrix murine MOE430 mouse array set. RNA was pooled from 3 mice in each dietary/treatment group.", "geo_gse_id": "E-GEOD-13705", "species": "mouse", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-13705/samples/"}