ArrayExpress Uploaderarrayexpress_sid8225controlstandardcontrolstandardcontrolstandardTNBSstandardTNBSstandardTNBSstandardcontrol2% curcumincontrol2% curcumincontrol2% curcuminTNBS2% curcuminTNBS2% curcuminTNBS2% curcumin07Curcumin is a potent anti-inflammatory compound capable of preventing chemically induced colitis in mice. We used microarray analysis to...18200517/profile/8773/arrayexpressuploader212colitiscolondiseaseDec.12, 2014FalseE-GEOD-13705_A-AFFY-23the-effects-of-dietary-curcumin-on-colonic-gene-exhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-13705The effects of dietary curcumin on colonic gene expression in TNBS-induced colitisNov.23, 2014Curcumin is a potent anti-inflammatory compound capable of preventing chemically induced colitis in mice. We used microarray analysis to detail the global programme of colonic gene expression in BALB/c mice fed standard or 2% curcumin-supplemented diet and treated with control or TNBS (trnitrobenzene-sulfonic acid, 2 mg/mouse) enema. Keywords: Diet and disease effect. 6-8 week old BALB/c mice were treated with respecive diet two days prior to enema administration (day 0) and sacrificed on day 7. Whole colon was dissected from mice and their wild-type littermates and total RNA isolated for microarray analysis using Affymetrix murine MOE430 mouse array set. RNA was pooled from 3 mice in each dietary/treatment group.E-GEOD-13705mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-13705/samples/