{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSE13692GSM344299": {}}, {"GSE13692GSM344300": {}}, {"GSE13692GSM344301": {}}, {"GSE13692GSM344302": {}}, {"GSE13692GSM344303": {}}, {"GSE13692GSM344305": {}}, {"GSE13692GSM344306": {}}, {"GSE13692GSM344307": {}}], "id": 5562, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Leukemia cells from mice with MLL-AF10 AML were fractionated into separate sub-populations on the basis of c-kit expression, which...", "geo_gse_id": "E-GEOD-13692", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 8, "tags": ["cell", "leukemia"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-human-mll-af10-myeloid", "geo_id_plat": "E-GEOD-13692_A-AFFY-45", "name": "Transcription profiling of human MLL-AF10 myeloid leukemia cellular subsets", "created": "Nov.10, 2014", "summary": "Leukemia cells from mice with MLL-AF10 AML were fractionated into separate sub-populations on the basis of c-kit expression, which correlates with MLL LSC frequency (Somervaille and Cleary, 2006).  The sorted AML sub-populations exhibited substantial differences in their frequencies of AML CFCs/LSCs (mean 14-fold) and morphologic features, consistent with a leukemia cell hierarchy with maturation through to terminally differentiated neutrophils. Experiment Overall Design: Leukemic splenocytes from four mice with MLL-AF10 AML were sub-fractionated in to c-kit high and c-kit negative sub-populations by FACS.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-13692", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-13692/samples/"}