6ArrayExpress Uploader0mouse5554arrayexpress_sidhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-13567The human cytomegalovirus (HCMV) encodes the chemokine receptor US28 that exhibits constitutive activity. NIH-3T3 cells stably...19318580/profile/8773/arrayexpressuploader04cellchemokinegenomeDec.12, 2014Falsetranscription-profiling-of-human-nih-3t3-us28-exprE-GEOD-13567_A-AFFY-45Transcription profiling of human NIH-3T3 US28-expressing and mock-transfected stablecell linesNov.10, 2014The human cytomegalovirus (HCMV) encodes the chemokine receptor US28 that exhibits constitutive activity. NIH-3T3 cells stably transfected with US28 present a pro-angiogenic and transformed phenotype both in vitro and in vivo. We used gene expression profiling to determine how US28 constitutive activity modulates expression of genes compared to mock-transfected cells. Experiment Overall Design: We isolated RNA from two different clonal stable cell lines of NIH-3T3 cells transfected either either mock or US28-WT and analysed these 4 RNA samples using Affymetrix mouse genome arrays.E-GEOD-13567http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-13567/samples/