Dataset: Transcription profiling of mouse AKR/J x PyMT F1 versus DBA/2J x PyMT F1 tumors

F1 hybrids from (AKR/J x FVB/NJ) and (DBA/2J x FVB/NJ) outcrosses display a 20-fold difference in mammary tumor metastatic capacity, due to differences in inherited polymorphisms. Expression studies were performed to determine whether polymorphism-driven gene expression signatures predictive of outcome could be generated from mouse tumor tissues Experiment Overall Design: Mammary tumors from adult F1 animals from (AKR/J x PyMT) and (DBA/2J x PyMT) outcrosses was collected and arrayed on Affymetrics chip to identify basal differences in gene expression between the different genotypes

Species:

mouse

Samples:

6

Source:

E-GEOD-13221

Updated:

Dec.12, 2014

Registered:

Nov.24, 2014