<?xml version="1.0" encoding="ASCII"?>
<biogps><data><item key="platform">6</item><item key="owner">ArrayExpress Uploader</item><item key="ownerprofile_id">arrayexpress_sid</item><item key="species">mouse</item><item key="factors"><item><item key="GSM313206"><item key="MOUSE MODEL">c-myc f2 N-myc f2 on a mixed background</item></item></item><item><item key="GSM313207"><item key="MOUSE MODEL">c-myc f2 M-Myc f2 on a mixed background </item></item></item><item><item key="GSM313206"><item key="MOUSE MODEL">c-myc f2 N-myc f2 on a mixed background</item></item></item><item><item key="GSM313209"><item key="MOUSE MODEL">MxCre c-myc f2 N-myc f2 on a mixed background</item></item></item><item><item key="GSM313209"><item key="MOUSE MODEL">MxCre c-myc f2 N-myc f2 on a mixed background</item></item></item><item><item key="GSM313209"><item key="MOUSE MODEL">MxCre c-myc f2 N-myc f2 on a mixed background</item></item></item></item><item key="id">5459</item><item key="pop_total">0</item><item key="source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-12467</item><item key="summary_wrapped">Analysis of HSCs from control and c-myc N-myc deficient long-term hematopoietic stem cells. HSCs lacking both c-myc and N-myc display...</item><item key="pubmed_id">19041778</item><item key="owner_profile">/profile/8773/arrayexpressuploader</item><item key="factor_count">1</item><item key="sample_count">6</item><item key="tags"/><item key="lastmodified">Dec.12, 2014</item><item key="is_default">False</item><item key="geo_gds_id"/><item key="slug">differentially-regulated-genes-in-control-and-c-my</item><item key="geo_id_plat">E-GEOD-12467_A-AFFY-45</item><item key="name">Differentially regulated genes in control and c-myc N-myc deficient LT-HSCs</item><item key="created">Nov.10, 2014</item><item key="summary">Analysis of HSCs from control and c-myc N-myc deficient long-term hematopoietic stem cells. HSCs lacking both c-myc and N-myc display increased apoptosis rates. Data provide insight into the molecular changes occuring upon complete loss of Myc activity, clarifying the resulting apoptotic mechanism and the role of Myc family proteins in HSCs.  LT-HSC (Lin-Sca1+CD150+CD48-) cells were sorted from the BM of MxCre c-myc flox2 N-myc flox2 (experimental) and c-myc flox2 N-myc flox2 (control) mice 3 days  after the last pI-pC injection. Each condition was analysed in triplicates, with each replicate consisting of a pool of 3 dKO mice or 2 control mice.</item><item key="geo_gse_id">E-GEOD-12467</item><item key="sample_source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-12467/samples/</item></data></biogps>
