Dataset: Differential gene expression in GBS6 cells after EWS-POU5F1 knockdown

Our objective is to clarify the function of EWS-POU5F1 chimera. Specifially, GBS6 cells were established from an undifferentiated bone sarcoma carrying translocation t(6;22)(p21;q12). The translocation resulted in a gene fusion between EWS and POU5F1. Gene expression analysis of t(6;22) undifferentiated sarcoma cell line GBS6 transfected with POU5F1 specific siRNA to investigate the function of EWS-POU5F1. Knockdown of EWS-POU5F1 using POU5F1 specific siRNAs. 3 control and 6 experimental replicates representing the same experiment repeated 3 times (1st, 2nd, 3rd).

Species:

human

Samples:

9

Source:

E-GEOD-12320

PubMed:

20203285

Updated:

Dec.12, 2014

Registered:

Sep.10, 2014