{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 8364, "factors": [{"GSE12310GSM309474": {}}, {"GSE12310GSM309475": {}}, {"GSE12310GSM309476": {}}, {"GSE12310GSM309477": {}}, {"GSE12310GSM309478": {}}, {"GSE12310GSM309479": {}}, {"GSE12310GSM309480": {}}, {"GSE12310GSM309481": {}}, {"GSE12310GSM309482": {}}, {"GSE12310GSM309483": {}}, {"GSE12310GSM309484": {}}, {"GSE12310GSM309485": {}}, {"GSE12310GSM309486": {}}, {"GSE12310GSM309487": {}}, {"GSE12310GSM309488": {}}, {"GSE12310GSM309489": {}}, {"GSE12310GSM309490": {}}, {"GSE12310GSM309491": {}}, {"GSE12310GSM309492": {}}, {"GSE12310GSM309493": {}}, {"GSE12310GSM309494": {}}, {"GSE12310GSM309495": {}}, {"GSE12310GSM309496": {}}, {"GSE12310GSM309497": {}}, {"GSE12310GSM309498": {}}, {"GSE12310GSM309499": {}}, {"GSE12310GSM309500": {}}, {"GSE12310GSM309501": {}}, {"GSE12310GSM309502": {}}, {"GSE12310GSM309503": {}}, {"GSE12310GSM309504": {}}, {"GSE12310GSM309505": {}}, {"GSE12310GSM309506": {}}, {"GSE12310GSM309507": {}}, {"GSE12310GSM309508": {}}, {"GSE12310GSM309509": {}}, {"GSE12310GSM309510": {}}, {"GSE12310GSM309511": {}}, {"GSE12310GSM309512": {}}], "ownerprofile_id": "arrayexpress_sid", "platform": 8, "summary_wrapped": "We created a mouse model where conditional expression of physiologic levels of an Mll-AF4 fusion oncogene induces development of acute...", "pubmed_id": 18977325, "geo_gse_id": "E-GEOD-12310", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 39, "tags": ["bone", "bone marrow"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-mouse-normal-lymphoid-p", "geo_id_plat": "E-GEOD-12310_A-AFFY-36", "name": "Transcription profiling of mouse normal lymphoid progenitors and MLL-AF4 leukemic lymphoblasts", "created": "Nov.24, 2014", "summary": "We created a mouse model where conditional expression of physiologic levels of an Mll-AF4 fusion oncogene induces development of acute lymphoblastic (ALL) or acute myeloid leukemias (AML). Immunophenotypic and gene expression analysis of the ALL cells demonstrated bone marrow replacement with B-precursor cells which express a gene expression profile that has significant overlap with profiles in human MLL-rearranged ALL. Experiment Overall Design: Total RNA from normal pro-B, pre-B, immature B and mature B lymphocytes, and from leukemic pre-B cells was isolated and hybridized to Affymetrix expresison microarrays.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-12310", "species": "mouse", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-12310/samples/"}