{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 2917, "factors": [{"GSE12108GSM305429": {"infect": "Francisella tularensis novicida"}}, {"GSE12108GSM305429": {"infect": "Francisella tularensis novicida"}}, {"GSE12108GSM305429": {"infect": "Francisella tularensis novicida"}}, {"GSE12108GSM305429": {"infect": "Francisella tularensis novicida"}}, {"GSE12108GSM305437": {"infect": "Francisella tularensis Schu S4"}}, {"GSE12108GSM305437": {"infect": "Francisella tularensis Schu S4"}}, {"GSE12108GSM305437": {"infect": "Francisella tularensis Schu S4"}}, {"GSE12108GSM305437": {"infect": "Francisella tularensis Schu S4"}}, {"GSE12108GSM305430": {"infect": "uninfected"}}, {"GSE12108GSM305430": {"infect": "uninfected"}}, {"GSE12108GSM305430": {"infect": "uninfected"}}, {"GSE12108GSM305430": {"infect": "uninfected"}}, {"GSE12108GSM305430": {"infect": "uninfected"}}, {"GSE12108GSM305430": {"infect": "uninfected"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Differential expression in human peripheral blood monocytes between F. novicida-infected and uninfected, and between Francisella...", "pubmed_id": 18698339, "geo_gse_id": "E-GEOD-12108", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 14, "tags": ["left", "peripheral"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-by-array-of-human-periph-6", "geo_id_plat": "E-GEOD-12108_A-AFFY-44", "name": "Transcription profiling by array of human peripheral blood mononuclear cells infected with Francisella tularensis", "created": "Sep.03, 2014", "summary": "Differential expression in human peripheral blood monocytes between F. novicida-infected and uninfected, and between Francisella tularensis tularensis isolate Schu S4 and uninfected. The goal was to examine genomewide transcriptional reponses to these two strains, and identify differentially-regulated genes that may help explain the virulence of Schu S4. Experiment Overall Design: Human monocytes were infected with the Schu S4 isolate of Francisella tularensis tularensis (n=4), with F. tularensis subspecies novicida isolate U112 (n=4) or were left uninfected (n=6).  Gene expression values were calculated using the gcrma package in R and BioConductor, and limma to identify differentially expressed genes.  Submitted here are expression values calculated using R 2.7.1 and BioConductor 2.2 (FreeBSD/amd64) but the original were done using R 2.6.1 and BioConductor 2.1 (FreeBSD/amd64).  Twelve other chips were pooled with these 14 for preprocessing.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-12108", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-12108/samples/"}