{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSE11796GSM298368": {}}, {"GSE11796GSM298386": {}}, {"GSE11796GSM298387": {}}, {"GSE11796GSM298388": {}}, {"GSE11796GSM298389": {}}, {"GSE11796GSM298390": {}}, {"GSE11796GSM298409": {}}, {"GSE11796GSM298410": {}}, {"GSE11796GSM298411": {}}, {"GSE11796GSM298412": {}}, {"GSE11796GSM298413": {}}, {"GSE11796GSM298414": {}}, {"GSE11796GSM298416": {}}, {"GSE11796GSM298417": {}}, {"GSE11796GSM298419": {}}, {"GSE11796GSM298421": {}}, {"GSE11796GSM298422": {}}, {"GSE11796GSM298423": {}}], "id": 5419, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Starting with our early global expression analyses of TCDD-treated human hepatoma cells {Puga, 2000 4679 /id}, the AHR transcriptional...", "geo_gse_id": "E-GEOD-11796", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 18, "tags": ["cell", "hepatoma"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-human-wild-type-and-mut", "geo_id_plat": "E-GEOD-11796_A-AFFY-45", "name": "Transcription profiling of human wild type and mutant hepatoma cells botg ligand-activated and -unactivated AHR", "created": "Nov.10, 2014", "summary": "Starting with our early global expression analyses of TCDD-treated human hepatoma cells {Puga, 2000 4679 /id}, the AHR transcriptional induction profile has been extensively studied, whether activated by TCDD, B[a]P or in the absence of exogenous ligands (reviewed in {Frericks, 2007 5618 /id}).  In addition to using prior knowledge to integrate expression profiles into the AHR gene target network, we performed a new set of expression profile analyses of wild type Hepa-1c1c7 and c35 cell lines and compared the responses in na\u00efve cells with responses in TCDD or B[a]P exposed cells for 8 hours.  Results of our expression array studies are in close agreement with current knowledge. Experiment Overall Design: Three biological replicates were each performed for wildype na\u00efve cells  (DMSO), TCDD activated cells, and B[a]P activated cells, and for c35 (AHR mutant) na\u00efve cells (DMSO), TCDD activated cells, and B[a]P activated cells.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-11796", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-11796/samples/"}