ArrayExpress Uploaderarrayexpress_sidmouse540406The molecular processes underlying the properties of ESC are yet unknown even when it's well established that LIF/STAT3 is neccesary for...E-GEOD-11628/profile/8773/arrayexpressuploader012Dec.12, 2014Falsewnt-lif-signalling-in-mescE-GEOD-11628_A-AFFY-45Wnt & LIF signalling in mESCNov.10, 2014The molecular processes underlying the properties of ESC are yet unknown even when it's well established that LIF/STAT3 is neccesary for the maintenance of pluripotency. Other pathways as Wnt are may be implicated in the regulation of the biological mechanisms in mESC. Work model: D3-ES cultivated with or without LIF and treated with chronic (7 days) low doses (50nM) of GSK3 β inhibitor (lithium). We used microarrays to detail the global profile of gene expression to identified different groups of up and down-regulated genes in the work model. mESC cultivated as it has been defined in the work model were prepared for RNA extraction and hybridization on Affymetrix microarrays. We analyzed 3 independent experiments per replicate, and we did three replicates per sample.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-11628http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-11628/samples/