ArrayExpress Uploader0286920controlM34controlF40controlF31controlM21controlF43controlM18controlF26controlM2988: Other (specify)F3106: HomeM5009: DeathM2106: HomeM3402: Skilled nursing facilityM3301: Inpatient rehabilitation facilityF2602: Skilled nursing facilityM2188: Other (specify)M4702: Skilled nursing facilityM4009: DeathM4801: Inpatient rehabilitation facilityF4502: Skilled nursing facilityM3402: Skilled nursing facilityM4306: HomeF5105: Home with servicesM4105: Home with servicesM2706: HomeM2801: Inpatient rehabilitation facilityM4102: Skilled nursing facilityF3306: HomeM2606: HomeM1606: HomeM5001: Inpatient rehabilitation facilityM3202: Skilled nursing facilityF3109: DeathM3106: HomeF5106: HomeF2706: HomeF4101: Inpatient rehabilitation facilityF3401: Inpatient rehabilitation facilityM4302: Skilled nursing facilityF5502: Skilled nursing facilityF4806: HomeF4902: Skilled nursing facilityF2702: Skilled nursing facilityF2401: Inpatient rehabilitation facilityM2202: Skilled nursing facilityF1606: HomeM5102: Skilled nursing facilityF4306: HomeM5502: Skilled nursing facilityM2602: Skilled nursing facilityM2002: Skilled nursing facilityM4505: Home with servicesM5402: Skilled nursing facilityF3702: Skilled nursing facilityM2706: HomeM5202: Skilled nursing facilityM3201: Inpatient rehabilitation facilityM4607: Another acute care facilityM2101: Inpatient rehabilitation facilityM2801: Inpatient rehabilitation facilityM4502: Skilled nursing facilityM3502: Skilled nursing facilityM2006: HomeM4002: Skilled nursing facilityM1902: Skilled nursing facilityM1806: HomeM3506: HomeM2006: HomeM2209: DeathF1805: Home with servicesM3202: Skilled nursing facilityM2502: Skilled nursing facilityM4406: HomeM4706: HomeM3002: Skilled nursing facilityF4706: HomeM2102: Skilled nursing facilityM4901: Inpatient rehabilitation facilityM3502: Skilled nursing facilityM2802: Skilled nursing facilityF5501: Inpatient rehabilitation facilityM1888: Other (specify)F4106: HomeF4902: Skilled nursing facilityF3102: Skilled nursing facilityM1606: HomeM5006: HomeM2401: Inpatient rehabilitation facilityM2202: Skilled nursing facilityM1906: HomeF1701: Inpatient rehabilitation facilityF4605: Home with servicesM2305: Home with servicesM3406: HomeF5406: HomeM2906: HomeM18controlM3307: Another acute care facilityF2006: HomeM4805: Home with servicesM4102: Skilled nursing facilityM2506: HomeM2505: Home with servicesM2501: Inpatient rehabilitation facilityM2702: Skilled nursing facilityM4001: Inpatient rehabilitation facilityM4502: Skilled nursing facilityM31controlF2309: DeathM1702: Skilled nursing facilityF4805: Home with servicesM3609: DeathM2101: Inpatient rehabilitation facilityM3506: HomeF3302: Skilled nursing facilityM2402: Skilled nursing facilityF3402: Skilled nursing facilityF2902: Skilled nursing facilityM19controlF4006: HomeM2906: HomeF3788: Other (specify)F4306: HomeM3601: Inpatient rehabilitation facilityF4002: Skilled nursing facilityF3301: Inpatient rehabilitation facilityF1701: Inpatient rehabilitation facilityF4306: HomeM1802: Skilled nursing facilityF45controlF2788: Other (specify)F4801: Inpatient rehabilitation facilityM2405: Home with servicesF3502: Skilled nursing facilityM1802: Skilled nursing facilityF2102: Skilled nursing facilityF5006: HomeF2106: HomeM3306: HomeM2102: Skilled nursing facilityM18controlM4006: HomeF1701: Inpatient rehabilitation facilityF4901: Inpatient rehabilitation facilityM2501: Inpatient rehabilitation facilityF2501: Inpatient rehabilitation facilityF2806: HomeM5101: Inpatient rehabilitation facilityM5206: HomeM5102: Skilled nursing facilityM2201: Inpatient rehabilitation facilityM18controlM4405: Home with servicesF1705: Home with servicesM3805: Home with servicesM4405: Home with servicesM2601: Inpatient rehabilitation facilityM3101: Inpatient rehabilitation facilityM2909: DeathM5402: Skilled nursing facilityF4302: Skilled nursing facilityF3902: Skilled nursing facilityF19controlM2188: Other (specify)M5202: Skilled nursing facilityF2806: HomeF2406: HomeF2801: Inpatient rehabilitation facilityF3401: Inpatient rehabilitation facilityM3605: Home with servicesM4001: Inpatient rehabilitation facilityM3402: Skilled nursing facilityM4106: HomeF41controlF35controlM30controlF20controlM26controlF34controlF28controlF23controlM32controlM37controlM19controlMarrayexpress_sid4Physiological, anatomical, and clinical laboratory analytic scoring systems (APACHE, Injury Severity Score (ISS)) have been utilized,...19593405E-GEOD-11375/profile/8773/arrayexpressuploader3184genomeleukocyteorganperipheralDec.12, 2014Falsea-genomic-score-prognostic-of-outcome-in-trauma-paE-GEOD-11375_A-AFFY-44A Genomic Score Prognostic of Outcome in Trauma PatientsSep.03, 2014Physiological, anatomical, and clinical laboratory analytic scoring systems (APACHE, Injury Severity Score (ISS)) have been utilized, with limited success, to predict outcome following injury. We hypothesized that a peripheral blood leukocyte gene expression score could predict outcome, including multiple organ failure, following severe blunt trauma. Contributor: The Inflammation and the Host Response to Injury Large Scale Collaborative Research Program Keywords: expression profiles cRNA derived from whole blood leukocytes obtained within 12 hours of hospital admission provided gene expression data for the entire genome that were used to create a gene expression score for each patient. Expression profiles from healthy volunteers were averaged to create a reference gene expression profile which was used to compute a difference from reference (DFR) score for each patient. This score described the overall genomic response of patients within the first 12 hours following severe blunt trauma. Regression models were used to compare the association of the DFR, APACHE and ISS scores with outcome.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-11375humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-11375/samples/