{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSE10971GSM277800": {"disease state": "high grade serous carcinoma", "genotype": "BRCA1/2 wildtype"}}, {"GSE10971GSM277809": {"disease state": "high grade serous carcinoma", "genotype": "BRCA1 3875delGTCT"}}, {"GSE10971GSM277812": {"disease state": "high grade serous carcinoma", "genotype": "BRCA1 mutation"}}, {"GSE10971GSM277801": {"disease state": "high grade serous carcinoma", "genotype": "Unknown"}}, {"GSE10971GSM277801": {"disease state": "high grade serous carcinoma", "genotype": "Unknown"}}, {"GSE10971GSM277801": {"disease state": "high grade serous carcinoma", "genotype": "Unknown"}}, {"GSE10971GSM277801": {"disease state": "high grade serous carcinoma", "genotype": "Unknown"}}, {"GSE10971GSM277801": {"disease state": "high grade serous carcinoma", "genotype": "Unknown"}}, {"GSE10971GSM277801": {"disease state": "high grade serous carcinoma", "genotype": "Unknown"}}, {"GSE10971GSM277812": {"disease state": "high grade serous carcinoma", "genotype": "BRCA1 mutation"}}, {"GSE10971GSM277812": {"disease state": "high grade serous carcinoma", "genotype": "BRCA1 mutation"}}, {"GSE10971GSM277801": {"disease state": "high grade serous carcinoma", "genotype": "Unknown"}}, {"GSE10971GSM277808": {"disease state": "high grade serous carcinoma", "genotype": "BRCA1 917delTT"}}, {"GSE10971GSM277788": {"disease state": "normal", "genotype": "BRCA1 5382insC"}}, {"GSE10971GSM277797": {"disease state": "normal", "genotype": "BRCA1 1293del40"}}, {"GSE10971GSM277798": {"disease state": "normal", "genotype": "BRCA1 185delAG"}}, {"GSE10971GSM277798": {"disease state": "normal", "genotype": "BRCA1 185delAG"}}, {"GSE10971GSM277798": {"disease state": "normal", "genotype": "BRCA1 185delAG"}}, {"GSE10971GSM277790": {"disease state": "normal", "genotype": "BRCA1 A1959T"}}, {"GSE10971GSM277798": {"disease state": "normal", "genotype": "BRCA1 185delAG"}}, {"GSE10971GSM277798": {"disease state": "normal", "genotype": "BRCA1 185delAG"}}, {"GSE10971GSM277793": {"disease state": "normal", "genotype": "BRCA2 C5910G"}}, {"GSE10971GSM277788": {"disease state": "normal", "genotype": "BRCA1 5382insC"}}, {"GSE10971GSM277798": {"disease state": "normal", "genotype": "BRCA1 185delAG"}}, {"GSE10971GSM277796": {"disease state": "normal", "genotype": "BRCA2 6174delT"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}, {"GSE10971GSM277776": {"disease state": "normal", "genotype": "not applicable"}}], "id": 2836, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "The purpose of this study was to identify molecular alterations potentially involved in predisposition to adnexal serous carcinoma...", "pubmed_id": 18593983, "geo_gse_id": "E-GEOD-10971", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 37, "tags": ["brca1", "carcinoma", "distal", "serous carcinoma"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-10971_A-AFFY-44", "slug": "transcription-profiling-by-array-of-human-non-mali", "geo_gds_id": "", "name": "Transcription profiling by array of human non-malignant fallopian tube epithelium and high grade serous carcinoma", "created": "Sep.03, 2014", "summary": "The purpose of this study was to identify molecular alterations potentially involved in predisposition to adnexal serous carcinoma (SerCa) in the non-malignant fallopian tube epithelium   (FTE) of BRCA1/2-mutation carriers, given recent evidence implicating the distal FTE as a common source for SerCa. Experiment Overall Design: We obtained and compared gene expression profiles of laser capture microdissected non-malignant distal FTE from 12 known BRCA1/2-mutation carriers (FTEb) and 12 control women  (FTEn) during the luteal and follicular phase, as well as 13 high grade tubal and ovarian SerCa.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10971", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10971/samples/"}