Dataset: Transcription profiling by array of human non-malignant fallopian tube epithelium and high grade serous carcinoma

The purpose of this study was to identify molecular alterations potentially involved in predisposition to adnexal serous carcinoma (SerCa) in the non-malignant fallopian tube epithelium (FTE) of BRCA1/2-mutation carriers, given recent evidence implicating the distal FTE as a common source for SerCa. Experiment Overall Design: We obtained and compared gene expression profiles of laser capture microdissected non-malignant distal FTE from 12 known BRCA1/2-mutation carriers (FTEb) and 12 control women (FTEn) during the luteal and follicular phase, as well as 13 high grade tubal and ovarian SerCa.

Species:

human

Samples:

37

Source:

E-GEOD-10971

PubMed:

18593983

Updated:

Dec.12, 2014

Registered:

Sep.03, 2014