{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSE10890GSM275974": {"compound": "none", "cell line": "BT549", "time": 0}}, {"GSE10890GSM275975": {"compound": "none", "cell line": "CAL851", "time": 0}}, {"GSE10890GSM275976": {"compound": "none", "cell line": "MDA175", "time": 0}}, {"GSE10890GSM275977": {"compound": "none", "cell line": "HS578T", "time": 0}}, {"GSE10890GSM275978": {"compound": "none", "cell line": "MCF7", "time": 0}}, {"GSE10890GSM275979": {"compound": "none", "cell line": "BT483", "time": 0}}, {"GSE10890GSM275980": {"compound": "none", "cell line": "EFM192A", "time": 0}}, {"GSE10890GSM275981": {"compound": "none", "cell line": "KPL1", "time": 0}}, {"GSE10890GSM275981": {"compound": "none", "cell line": "KPL1", "time": 0}}, {"GSE10890GSM275983": {"compound": "none", "cell line": "SKBR3", "time": 0}}, {"GSE10890GSM275984": {"compound": "none", "cell line": "CAL51", "time": 0}}, {"GSE10890GSM275984": {"compound": "none", "cell line": 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{"GSE10890GSM276036": {"compound": "none", "cell line": "SW527", "time": 0}}, {"GSE10890GSM276037": {"compound": "none", "cell line": "MDA-MB231", "time": 0}}, {"GSE10890GSM276037": {"compound": "none", "cell line": "MDA-MB231", "time": 0}}, {"GSE10890GSM276037": {"compound": "none", "cell line": "MDA-MB231", "time": 0}}, {"GSE10890GSM276040": {"compound": "control for mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 18}}, {"GSE10890GSM276040": {"compound": "control for mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 18}}, {"GSE10890GSM276040": {"compound": "control for mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 18}}, {"GSE10890GSM276043": {"compound": "mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 18}}, {"GSE10890GSM276043": {"compound": "mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 18}}, {"GSE10890GSM276043": {"compound": "mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 18}}, {"GSE10890GSM275978": {"compound": 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"ESR1 siRNA control", "cell line": "MCF7", "time": 18}}, {"GSE10890GSM276058": {"compound": "ESR1 siRNA", "cell line": "MCF7", "time": 18}}, {"GSE10890GSM276058": {"compound": "ESR1 siRNA", "cell line": "MCF7", "time": 18}}, {"GSE10890GSM276004": {"compound": "none", "cell line": "BT474", "time": 0}}, {"GSE10890GSM276004": {"compound": "none", "cell line": "BT474", "time": 0}}, {"GSE10890GSM276062": {"compound": "none", "cell line": "MDA-MB231", "time": 72}}, {"GSE10890GSM276062": {"compound": "none", "cell line": "MDA-MB231", "time": 72}}, {"GSE10890GSM276062": {"compound": "none", "cell line": "MDA-MB231", "time": 72}}, {"GSE10890GSM276065": {"compound": "control for mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 72}}, {"GSE10890GSM276065": {"compound": "control for mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 72}}, {"GSE10890GSM276067": {"compound": "control for mir-221/222 inhibitor ", "cell line": "MDA-MB231", "time": 72}}, {"GSE10890GSM276068": {"compound": "mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 72}}, {"GSE10890GSM276068": {"compound": "mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 72}}, {"GSE10890GSM276068": {"compound": "mir-221/222 inhibitor", "cell line": "MDA-MB231", "time": 72}}, {"GSE10890GSM276071": {"compound": "none", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276071": {"compound": "none", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276071": {"compound": "none", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276074": {"compound": "control for mir-221/222 mimic", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276074": {"compound": "control for mir-221/222 mimic", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276074": {"compound": "control for mir-221/222 mimic", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276077": {"compound": "mir-221/222 mimic", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276077": {"compound": "mir-221/222 mimic", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276077": {"compound": "mir-221/222 mimic", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276080": {"compound": "control for ESR1 siRNA", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276080": {"compound": "control for ESR1 siRNA", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276080": {"compound": "control for ESR1 siRNA", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276083": {"compound": "ESR1 siRNA", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276083": {"compound": "ESR1 siRNA", "cell line": "MCF7", "time": 72}}, {"GSE10890GSM276083": {"compound": "ESR1 siRNA", "cell line": "MCF7", "time": 72}}], "id": 2832, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "mRNA breast cancer cell lines were profiled to study the function of hsa-mir-221 and hsa-mir-222. MCF7 cell lines were profiled after...", "geo_gse_id": "E-GEOD-10890", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 3, "sample_count": 112, "tags": ["breast", "breast cancer", "cancer", "cell", "line"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-by-array-of-human-breast-3", "geo_id_plat": "E-GEOD-10890_A-AFFY-44", "name": "Transcription profiling by array of human breast cancer cell lines after treatment with miR-221/222 mimics or inhibitors", "created": "Sep.03, 2014", "summary": "mRNA breast cancer cell lines were profiled to study the function of hsa-mir-221 and hsa-mir-222. MCF7 cell lines were profiled after treatment with mir-221/222 mimics, and compared to profiles with transfection controls. Similarly, MDA-MB-231 cell lines were profiled after treatment with mir-221/222 inhibitors, and compared to profiles with transfection controls. Since ESR1 is a predicted target of mir-221/222 we also profiled MCF7 cell lines after disrupting ESR1 with an siRNA. Other breast cancer cell lines are provided because all cell lines were normalized together. Experiment Overall Design: mRNA breast cancer cell line profiles with some samples in duplicate or triplicate. See summary for more information.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10890", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10890/samples/"}