ArrayExpress Uploader0mouse8340arrayexpress_sid8Ablation of the Srf gene in dopaminoceptive neurons of the brain was performed using the Cre/loxP system, with the recombinase expressed...E-GEOD-10870/profile/8773/arrayexpressuploader012brainstriatumDec.12, 2014Falserole-of-srf-in-activity-regulated-transcription-inE-GEOD-10870_A-AFFY-36Role of SRF in activity-regulated transcription in the striatum of the brainNov.24, 2014Ablation of the Srf gene in dopaminoceptive neurons of the brain was performed using the Cre/loxP system, with the recombinase expressed from a BAC-derived Drd1a promoter. Our goal was to analyze how loss of SRF will affect acitivity-regulated transcription induced by strong stimulation, i.e. cocaine. Keywords: Treatment x Genotype Animals were injected i.p. with either 25 mg/kg cocaine or saline and sacrificed after one hour by cervical dislocation. Expression profiling was performed using total RNA isolated from the striatum.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10870http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10870/samples/