ArrayExpress Uploader0mouse8339arrayexpress_sid8Ablation of the Camk4 gene in dopaminoceptive neurons of the brain was performed using the Cre/loxP system, with the recombinase...E-GEOD-10869/profile/8773/arrayexpressuploader018brainstriatumDec.12, 2014Falsetranscription-profiling-of-mouse-with-abalated-dopE-GEOD-10869_A-AFFY-36Transcription profiling of mouse with abalated dopaminoceptive neurons to examine the effects of CaMKIV loss on cocaine-induced gene expression in the striatumNov.24, 2014Ablation of the Camk4 gene in dopaminoceptive neurons of the brain was performed using the Cre/loxP system, with the recombinase expressed from a BAC-derived Drd1a promoter. Our goal was to analyze how loss of CaMKIV will affect acitivity-regulated transcription induced by strong stimulation, i.e. cocaine. Experiment Overall Design: Animals were injected i.p. with either 25 mg/kg cocaine or saline and sacrificed after one hour by cervical dislocation. Expression profiling was performed using total RNA isolated from the striatum.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10869http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10869/samples/