{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "mouse", "factors": [{"GSE10765GSM271858": {}}, {"GSE10765GSM271859": {}}, {"GSE10765GSM271860": {}}, {"GSE10765GSM271861": {}}, {"GSE10765GSM271854": {}}, {"GSE10765GSM271855": {}}, {"GSE10765GSM271856": {}}, {"GSE10765GSM271857": {}}, {"GSE10765GSM271850": {}}, {"GSE10765GSM271851": {}}, {"GSE10765GSM271852": {}}, {"GSE10765GSM271853": {}}], "id": 5333, "pop_total": 0, "platform": 6, "summary_wrapped": "IL-1R-associated kinases (IRAKs) participate in Toll-like receptor (TLR) signal transduction. MALP-2 is a TLR2 ligand, and stimulation of...", "geo_gse_id": "E-GEOD-10765", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 12, "tags": [], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-mouse-malp-2-stimulated", "geo_id_plat": "E-GEOD-10765_A-AFFY-45", "name": "Transcription profiling of mouse  MALP-2-stimulated macrophages FROM wild-TYPE, IRAK-2-/- AND  IRAK-1-/IRAK-2-/- animals", "created": "Nov.10, 2014", "summary": "IL-1R-associated kinases (IRAKs) participate in Toll-like receptor (TLR) signal transduction. MALP-2 is a TLR2 ligand, and stimulation of macrophages with MALP-2 activates expression of various genes including proinflammatory cytokines. We used microarrays to examine influence of IRAK-2 or IRAK-1/IRAK-2 deficiency in MALP-2-inducible gene expression. Experiment Overall Design: Peritoneal macrophages from wild-type, IRAK-2-/- and IRAK-1/IRAK-2 mice were stimulated with MALP-2 for 0, 2, 4, and 8 hours, followed by RNA extraction. Then hybridization on affymetrix microarrays was performed.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10765", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10765/samples/"}