ArrayExpress Uploaderarrayexpress_sidmouse527306Most of the genes were self-tolerized by Pam3CSK4 and MDP but there was no or minimal cross-tolerization. The transcriptome induced via...E-GEOD-10182/profile/8773/arrayexpressuploader07Dec.12, 2014FalseE-GEOD-10182_A-AFFY-45transcription-profiling-of-mouse-naive-and-toleranTranscription profiling of mouse naive and tolerant macrophages treated with MDP- and Pam3CSK4Nov.10, 2014Most of the genes were self-tolerized by Pam3CSK4 and MDP but there was no or minimal cross-tolerization. The transcriptome induced via Nod2 stimulation is greatly expanded in TLR2-tolerant macrophages. Experiment Overall Design: Genes induced by Pam3CSK4 or MDP were selected based on a three-fold increase over expression levels in unstimulated macrophages. Tolerized genes are defined as genes downregulated more than 2-fold in tolerant macrophages stimulated with Pam3CSK4 or MDP.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10182http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10182/samples/