{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSE10094GSM254997": {}}, {"GSE10094GSM255003": {}}, {"GSE10094GSM255001": {}}, {"GSE10094GSM255004": {}}], "id": 5268, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Following infection with LCMV, CD4+ SMARTA TCR transgenic cells (specific for the gp61-80 epitope of the LCMV glycoprotein) rapidly...", "geo_gse_id": "E-GEOD-10094", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 4, "tags": ["cell", "glycoprotein"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcription-profiling-of-mouse-smarta-transgenic", "geo_id_plat": "E-GEOD-10094_A-AFFY-45", "name": "Transcription profiling of mouse SMARTA transgenic cells in response to LCMV or Lm-gp61 infection", "created": "Nov.10, 2014", "summary": "Following infection with LCMV, CD4+ SMARTA TCR transgenic cells (specific for the gp61-80 epitope of the LCMV glycoprotein) rapidly expand, become effector cells, and go on to form a long-lived memory population.  Following infection with a recombinant Listeria monocytogenes expressing the LCMV epitope gp61-80, SMARTA cells also expand but display defective effector differentiation and fail to form memory.  In an attempt to understand the signals required for CD4 T cell memory differentiation, we compared gene expression by SMARTA cells at the peak of the primary response following either Lm-gp61 or LCMV infection. Experiment Overall Design: SMARTA cells were purified at day 7 post-infection with either LCMV or Lm-gp61.  SMARTA cells were sorted on the basis of Thy1.1 expression using a FACSAria.  Cells were sorted through the machine twice to enhance purity.  Two biological replicates of each group are provided.  Each replicate represents the results of SMARTA pooled from three animals.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10094", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-10094/samples/"}